| 翻訳と辞書 |
| Capnocytophaga canimorsus ： ウィキペディア英語版 |
Capnocytophaga canimorsus
''Capnocytophaga canimorsus'' is a fastidious, slow-growing Gram-negative rod of the genus ''Capnocytophaga''.〔Pers C, Gahrn-Hansen B, and Frederiksen W. 1996. ''Capnocytophaga canimorsus'' Septicemia in Denmark, 1982-1995: Review of 39 Cases. ''Clinical Infectious Diseases'' 23: 71-75.〕〔Brenner DJ, Hollis DG, Fanning GR, and Weaver RE. 1989. ''Capnocytophaga canimorsus'' sp. nov. (Formerly CDC Group DF-2), a Cause of Septicemia following Dog Bite, and ''C. cynodegmi'' sp. nov., a Cause of Localized Wound Infection following Dog Bite. ''Journal of Clinical Microbiology'' 27 (2): 231-235.〕 It is a commensal bacterium in the normal gingival flora of canine and feline species. Transmission may occur through bites, licks,or even close proximity with animals.〔Fischer LJ, Weyant RS, White EH and Quinn FD. Intracellular Multiplication and Toxic Destruction of Cultured Macrophages by ''Capnocytophaga canimorsus''. ''Infection and Immunity'' 63 (9): 3484-3490.〕 ''C. canimorsus'' generally has low virulence in healthy individuals,〔Lion C, Escande F and Burdin JC. 1996. ''Capnocytophaga canimorsus'' Infections in Human: Review of the Literature and Cases Report. ''European Journal of Epidemiology'' 12 (5): 521-533.〕 but has been observed to cause severe illness in persons with pre-existing conditions. The pathogenesis of ''C. canimorsus'' is still largely unknown, but increased clinical diagnoses have fostered an interest in the bacillus. Treatment with antibiotics is effective in most cases, but the most important yet basic diagnostic tool available to clinicians remains the knowledge of recent exposure to canines or felines.〔 Very little is known about the pathogenesis of this zoonotic pathogen.
==History==
''Capnocytophaga canimorsus'' was first observed in 1976 by Bobo and Newton. The pair isolated a previously unknown Gram-negative bacteria from a patient presenting with meningitis in addition to septicemia. The patient had been previously exposed to two canine bites on two consecutive days from two different dogs. Noting the coincidence between the timing of the bites with the onset of symptoms, Butler et al. analyzed 17 similar cases of patients presenting with either septicemia or meningitis from 1961-1975. The cases had been sent to the CDC for examination due to the presence of an unknown Gram-negative bacillus isolated from infected individuals. Butler notified the CDC of the high incidence of dog bites in connection with the infections. The CDC could not identify the organism and so they applied the name CDC group DF-2. DF-2 stands for Dysgonic fermenter, meaning that the bacteria is a slow-growing, fermentative bacillus. In 1989, while analyzing the properties of the unknown bacteria, Weaver et al. noted many similarities to bacteria of the genus ''Capnocytophaga''. Later that same year, Brenner et al. proposed the name ''Capnocytophaga canimorsus'' after examining the morphology, G+C% content and motility of the bacteria.〔
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
■ウィキペディアで「Capnocytophaga canimorsus」の詳細全文を読む
スポンサード リンク
| 翻訳と辞書 : 翻訳のためのインターネットリソース |
Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.
|
|